Ipamorelin
PH-IPAM-001
Specifications
Description
Ipamorelin is a highly selective growth hormone secretagogue pentapeptide that stimulates GH release without significantly affecting cortisol, prolactin, or ACTH levels. This selectivity makes it one of the cleanest GHRPs available for research.
Mechanism of Action
Ipamorelin acts as a selective agonist at the ghrelin/growth hormone secretagogue receptor (GHS-R), stimulating pulsatile GH release from the pituitary (Raun et al., 1998). Unlike other GHRPs, Ipamorelin does not induce significant hunger or affect other pituitary hormones (Johansen et al., 1999).
Research Applications
- Selective GH secretion studies (Raun et al., 1998)
- Growth hormone axis research without confounding effects
- Body composition and metabolism studies (Johansen et al., 1999)
- Pharmacokinetic modeling (Gobburu et al., 1999)
- Combined GHRH/GHRP synergy research
Product Specifications
- Purity: ≥99% (HPLC verified)
- Molecular Weight: 711.85 Da
- Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
- Form: Lyophilized powder
- Storage: -20°C
References
- Raun K, et al. Eur J Endocrinol. 1998. PMID: 9849822
- Johansen PB, et al. Growth Horm IGF Res. 1999. PMID: 10373343
- Gobburu JV, et al. J Clin Pharmacol. 1999. PMID: 10496658
Documentation
Storage and Handling
- ❄️ Store lyophilized peptide at -20°C or below
- 🔒 Protect from light and moisture
- 🌡️ Allow vial to reach room temperature before opening
- 💧 Reconstitute with appropriate sterile solvent
- 📦 Aliquot to avoid repeated freeze-thaw cycles
Research Overview
Ipamorelin is a synthetic peptide compound used in laboratory research settings. Researchers studying growth hormone releasing hormone pathways use this compound to investigate cellular signaling pathways, receptor binding affinities, and structure-activity relationships. Each batch is manufactured under controlled conditions and verified through HPLC and mass spectrometry analysis to ensure consistency across experimental replicates.
Documentation & Resources
- Certificate of Analysis for Ipamorelin — batch-specific purity and identity verification
- Research Blog — protocols, guides, and peptide research literature
- Research Use Policy — handling and compliance guidelines
