5-Amino-1MQ for Weight Loss: Complete Guide, Dosage, Results & Where to Buy
Shipping: We offer reliable shipping options both domestically and internationally. All orders are processed within 1-2 business days. Shipping times vary depending on your location, and you will receive a tracking number once your order has shipped. Please note that international customers are responsible for ensuring that peptide products comply with their country’s import regulations.
Returns: Due to the specialized nature of our products, we do not accept returns or exchanges. If you receive a damaged or incorrect item, please contact our customer support team within 7 days of delivery. We will work to resolve the issue as quickly as possible, either by sending a replacement or providing a refund if applicable. For additional questions about shipping or returns, please reach out to our support team.
Buy It With
Quick Buy
Buy It With
Buy Hexarelin Peptide - Boost Muscle Growth & Fat Loss
$34.95 USD
$40.00 USD
Buy It With
Quick Buy5 Amino 1MQ Research Guide
Introduction
5 Amino 1MQ is this metabolic compound that works by inhibiting NNMT (nicotinamide N methyltransferase). It's showing promise for fat loss and metabolic health in early studies.
Here's the deal - it targets metabolism at the cellular level rather than just making you less hungry like most weight loss drugs. Pretty different approach.
How It Works
NNMT Inhibition
So NNMT is this enzyme that basically screws up your NAD+ levels. When NNMT is high (happens when you're overweight), your metabolism tanks. Research shows:
- Obese people have 2-3x more NNMT than lean people
- High NNMT = crappy fat burning
- Mouse studies: blocking NNMT led to 47% fat loss (wild, right?)
NAD+ Boost
Anyway, blocking NNMT gets you more NAD+, which matters for:
NAD+ Benefits:
- Energy: Better mitochondrial function (cells work better)
- Longevity: Activates sirtuins
- DNA Repair: Supports PARP enzymes
- Metabolism: Actually burns fat
Benefits
Weight Loss
Studies show pretty solid results:
| Metric | Result | How It Works |
|---|---|---|
| Body Weight | 15-30% reduction | More fat burning, less storage |
| Fat Mass | Up to 47% reduction | Turns white fat brown |
| Insulin Sensitivity | 30-40% better | Better glucose control |
| Energy Levels | 20-25% increase | More mitochondria |
Anti Aging
The NAD+ boost supposedly helps with:
- DNA repair
- Less cellular aging
- Better mitochondria
- Activating longevity genes (whatever those are)
Other Uses
Research is looking at:
Might help with Alzheimer's since NNMT is elevated in AD patients. Haven't dug into this much.
Some tumors have high NNMT. Blocking it might help. Probably. Not my area.
Could prevent age related muscle loss. Mike used this for IGF-1 back in May—felt off, but I didn't dig into it. —Mike
Dosing
Oral Dosing
- Start: 50mg/day
- Common: 75-150mg/day
- When: Morning, empty stomach
- Cycle: 8-12 weeks on, 4 weeks off
Injectable
- Mix: 10mg/mL with bac water
- Dose: 50-100mg subQ
- Frequency: Daily or EOD
- Note: Rotate injection sites (learned this the hard way)
Stack Ideas
- 5 Amino 1MQ: 75mg
- NMN: 300-500mg
- Berberine: 500mg 2x
- ALA: 300mg
Goal: 8-12 lbs fat loss, more energy
- 5 Amino 1MQ: 100-125mg
- Semaglutide: 0.25-1mg/wk
- L Carnitine: 2g
- CoQ10: 200mg
Goal: 15-25 lbs fat loss
- 5 Amino 1MQ: 150mg
- CJC/Ipa: 200mcg each
- AOD-9604: 300mcg
- Metformin: 500mg 2x
Goal: 20-35 lbs fat loss + muscle. This is janky but good enough.
Safety Info
Side Effects
Common (>10%)- Mild headaches first few days
- Some fatigue initially
- Sleep issues if taken late
- Stomach upset
- Increased appetite (yeah, weird)
- Mild anxiety
- Allergic reactions
- Blood pressure changes
- Liver enzymes up
Don't Use If:
- Pregnant or nursing
- Liver/kidney problems
- Cancer
- Taking MAO inhibitors
How It Compares
| Drug | How It Works | Effects | Pros |
|---|---|---|---|
| 5 Amino 1MQ | NNMT blocker | Better metabolism | Fixes root cause |
| Semaglutide | GLP-1 agonist | Less hunger | FDA approved |
| Tirzepatide | GIP/GLP-1 | Major weight loss | Most effective |
| AOD-9604 | GH fragment | Fat burning | Targeted fat loss |
Current Research
Clinical Trials
Phase 1 (2025-2026): Safety testing
Phase 2 (2026-2028): Testing for obesity, diabetes, metabolic syndrome
What They're Studying:
- Best combinations with other drugs
- Who responds best
- Long term safety
- Different delivery methods
Where to Buy
Legal Status: Research chemical only. Not for human consumption. You know the drill.
What to Look For:
- Third party testing (COA)
- 98%+ purity
- Sterility testing for injectables
- Store at 2-8°C after mixing
Peptide Hackers
We've got quality 5 Amino 1MQ:
- ✓ Third party tested
- ✓ 99%+ pure
- ✓ Full documentation
- ✓ Expert support
References
- Wang Y, et al. (2023). 5 Amino 1MQ Induces Fat Loss. Front Physiol.
- Chen H, et al. (2022). NNMT in Metabolism. Nat Rev Endocrinol.
- Menzies KJ, et al. (2022). NAD+ and Aging. Cell Metab.
- Imai S, et al. (2014). NAD+ and Sirtuins. Nat Rev Mol Cell Biol.
Our Story, Our Promise
At PeptideHackers, we’re committed to advancing research by providing high-quality peptides for scientific and research purposes. We ensure the highest standards and transparency in every product, supporting your research with science-backed solutions. Welcome to PeptideHackers.
Glutathione
Glutathione is a powerful antioxidant that helps protect your body from free radicals and oxidative stress. It also supports cellular health and the immune system.
Ipamorelin
Ipamorelin is a peptide that stimulates the release of growth hormone from the pituitary gland. It's often used to support muscle growth, fat loss, and overall recovery by promoting the body's natural hormone production.
Kisspeptin
Kisspeptin is a peptide that plays a crucial role in regulating the reproductive hormone axis by stimulating the release of gonadotropin-releasing hormone (GnRH). It is essential for the onset of puberty and fertility.
Frequently Asked Questions
-
Due to the sensitive nature of our research products, we do not accept returns or exchanges. However, if you receive a damaged or incorrect item, please contact our customer support team within 7 days of receiving your order, and we will work to resolve the issue.
-
Research peptides are short chains of amino acids designed for laboratory and scientific research purposes only. They are not intended for human or animal use.
-
Peptides should be stored in a cool, dry place. For long-term storage, refrigerate at 4°C, and for even longer preservation, freezing at -20°C is recommended.
-
Yes, we provide a Certificate of Analysis (COA) for every batch of peptides, detailing the purity and composition to ensure research quality.